The United States is experiencing a decrease in respiratory virus cases but is witnessing a rise in new COVID-19 variants, known as the FLiRT variants. The dominant variant, KP.2, has surpassed the previous omicron subvariant, JN.1, and now accounts for a quarter of COVID-19 cases in the country. Other FLiRT variants like KP.1.1 are also circulating, although to a lesser extent. This increase in variants has raised concerns about a potential summer wave of infections.
The FLiRT variants, KP.2 and KP.1.1, are mutations of the JN.1 strain and have been found to be more transmissible due to additional mutations that give them an advantage over previous variants. These new variants belong to the omicron family and are evolving at a faster rate than other viruses like influenza. Initial data suggests that KP.2 may be more transmissible and is better at evading pre-existing immunity in the population, which raises concerns about vaccine effectiveness.
It is still uncertain whether the FLiRT variants will lead to a summer surge, as COVID-19 continues to circulate at varying levels throughout the year. Factors such as low vaccination rates, waning immunity, and the ability of the variants to take hold in the population will determine the future trajectory of the pandemic. While test positivity rates are currently low and hospitalizations have decreased, experts are cautious about the potential for a resurgence of cases in the coming months.
The symptoms of the FLiRT variants are similar to those caused by the previous omicron strains, with the severity of symptoms often dependent on a person’s underlying health and immunity. Laboratory studies suggest that current vaccines provide partial protection against KP.2 and other FLiRT variants, but an updated vaccine may be necessary in the future. Early data indicates that vaccination can still prevent severe disease, hospitalization, and complications from COVID-19, making it crucial for public health efforts.
While it is too early to know how the FLiRT variants will impact the summer months, individuals can take steps to protect themselves and others from COVID-19. Following CDC guidelines, such as staying up to date with vaccines, testing for COVID-19 if symptomatic, practicing good hygiene, improving ventilation, wearing masks in crowded indoor spaces, and maintaining social distancing, can help prevent the spread of the virus. Despite the uncertainty surrounding the new variants, taking proactive measures can help mitigate the potential impact of a summer wave of infections.
