Individuals with life-shortening genes can potentially extend their lifespan by adopting healthy lifestyle habits, according to new research. The study, published in the journal BMJ Evidence Based Medicine, found that people with unhealthy lifestyles and genetic predispositions were twice as likely to die prematurely compared to those with good habits and genes. Factors such as not smoking, physical activity, sleep, and diet were highlighted as having the greatest impact on longevity. The study suggested that individuals could reduce the effects of life-shortening genes by over 60% through actions such as quitting smoking, moderating alcohol consumption, staying active, getting enough sleep, and following a healthy diet.
Genes can influence the risk of dying from various diseases, such as cancer, heart disease, and diabetes, among others. However, individuals with a high genetic risk could potentially add nearly 5.5 years to their lifespan by adopting a healthy lifestyle starting at age 40. Experts emphasize the importance of lifestyle choices in determining longevity, with factors such as nutrition, movement, smoking, and sleep playing significant roles. The research challenges the notion that genetics alone determine lifespan, indicating that individuals have greater control over their fate through lifestyle choices.
The study involved over 350,000 adults recruited to the UK Biobank between 2006 and 2010, with their health tracked until 2021. Researchers used a polygenic risk score tool to assess participants’ overall genetic risk, categorizing them based on lifespan risks and lifestyles. The study found that individuals genetically predisposed to early death were 21% more likely to die during the study period, while those with unhealthy lifestyles faced a 78% higher risk of premature death. Participants with both unhealthy habits and genetic predispositions were twice as likely to die as those with healthy habits and favorable genetic profiles.
Various studies have highlighted the impact of lifestyle choices on lifespan, suggesting that adopting a healthy lifestyle, even later in life, can lower mortality risk and extend life expectancy. Public health policies promoting healthy lifestyles are seen as crucial in complementing traditional healthcare efforts and mitigating the influence of genetic factors on human lifespan. Experts stress the role of empowerment in taking control of one’s health, with sustainable changes in habits being key to long-term success. Encouraging people to engage in activities they enjoy and that fit into their schedule can increase adherence and lead to positive outcomes in the long run.
Research from the Chinese Center for Disease Control and Prevention and San Diego State University has further underlined the importance of a healthy lifestyle in improving longevity. Even individuals with a genetic predisposition to shorter or longer lifespans can benefit from positive lifestyle behaviors such as regular exercise and reduced sedentary time. The findings challenge the notion of pre-destined lifespans based solely on genetics, suggesting that individuals have significant control over their health and longevity through lifestyle choices. By emphasizing the role of empowerment and sustainable changes, researchers hope to inspire individuals to take ownership of their health and well-being for a longer and healthier life.
